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The aerosol can contain various chemicals, including nicotine, flavorings, and additives

Biology has traditionally started at the top, viewing a living organism as a complex biochemical machine, and worked analytically downwards from there through organs, tissues, cells, organelles, membranes, and finally molecules in its pursuit of the mechanisms of life

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The main difference between open - and closed - system e-cigarettes is the way the e-liquid is delivered to the heating mechanism of the device